Of course there will be unforeseen consequences! Does no one know anything about the nature of complex, dynamic, recursive systems? You can’t just pull out one Jenga piece and assume the tower will remain unbothered.
The real question is: does the EPA’s approval indemnify this company? If these mosquitoes result in some damage, who is on the hook to fix it?
In a real world of accountability, this company releasing GM mosquitoes would have to float a bond and pay for insurance to protect themselves from damages and to make property owners and downstream victims whole. They’d share in profits and in loss.
In this world, the EPA just says yeah go for it, we got you.